What Folic Acid tablets are and what
DESCRIPTION: Folic acid, USP, N- [ p-[[(2-amino-4- hydroxy-6-pteridinly) methyl]-amino] benzoyl]-L glutamic acid, is a B complex vitamin containing a pteridine moiety linked by a methylene bridge to para-aminobenzoic acid, which is joined by peptide linkage to a glutamic acid. Conjugates of folic acid, USP are present in a wide variety of foods, particularly liver, kidneys, yeast, and leafy green vegetables. Commercially available folic acid, USP is prepared synthetically. Folic Acid occurs as a yellow or yellowish-orange crystalline powder and is very slightly soluble in water and insoluble in alcohol. Folic Acid is readily soluble in dilute solutions of alkali hydroxides and carbonates, and solutions of the drug maybe prepared with the aid of sodium hydroxide or sodium carbonate, thereby forming the soluble salt of folic acid, USP (sodium folate). Aqueous solutions of folic acid, USP are heat sensitive and rapidly decompose in the presence of light and/or riboflavin; solutions should be stored in a cool place protected from light. The structure formula of folic acid, USP is as follows:
Folic Acid Structural Formula:
C 19H 19N 7O 6 M.W.441.40
They are used for Folic Acid belongs to the vitamin B group. Folic Acid tablets may be used:
- folate deficiency anaemia caused by poor diet, poor absorption of food (such as in coeliac disease or a digestive disorder called sprue) or increased use of folate in the body (as in pregnancy)
- folate deficiency caused by some medicines (e.g., Those used to treat epilepsy such as phenytoin, phenobarbital and primidone)
- folate deficiency caused by long-term red blood cell damage or kidney dialysis
- neural tube defects in babies (e.g., spina bifida), where women are at risk of having an affected child.
What you need to know before you take Folic Acid tablets
Do not take Folic Acid tablets and tell your doctor if you have:
- an allergy (hypersensitivity) to folic acid or any of the other ingredients in the tablets (see section 6)
- an untreated vitamin B12 deficiency such as in certain anaemias and lifelong vegetarians
- pernicious anaemia (a form of anaemia caused by lack of vitamin B12 ) or another condition caused by vitamin B12 deficiency
- a malignant (cancerous) disease.
How to take Folic Acid tablets
Always take Folic Acid tablets exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure. Swallow the tablets with water.
Adults (including the elderly):
- To treat folate deficiency anaemia: 5mg a day for 4 months, which may be increased up to a maximum of 15mg a day.
- To prevent folate deficiency caused by some medicines: 5mg a day for 4 months, which may be increased up to a maximum of 15mg a day.
- To prevent folate deficiency caused by long-term red blood cell damage or kidney dialysis: 5mg every 1-7 days.
- To prevent neural tube defects in babies, where women are at risk of having an affected child: 5mg a day started before conception and continued throughout the first three months.
- To treat folate deficiency during pregnancy: 5mg a day continued to birth.
Use in children and adolescents:
For young children a more suitable form of the medicine should be used.
- To treat folate deficiency anaemia: Children 1-18 years old: 5mg a day for 4 months. The maintenance dose is 5mg every 1-7 days.
- To treat haemolytic anaemia and metabolic disorders: Children 1-12 years old: 2.5mg-5mg once a day. Children 12-18 years old: 5-10mg once a day.
- To prevent folate deficiency in kidney dialysis: Children 1-12 years old: 250micrograms per kg of body weight (up to a maximum of 10mg) once a day. Children 12-18 years old: 5-10mg once a day.
If you take more than you should
If you (or someone else) swallow a lot of the tablets at the same time, or you think a child may have swallowed any, contact your nearest hospital casualty department or tell your doctor immediately.
If you forget to take the tablets
If you forget to take a dose take it as soon as you remember it and then take the next dose at the right time. Do not take a double dose to make up for a forgotten dose.
Possible side effects
Like all medicines, Folic Acid tablets can cause side effects, although not everybody gets them. Tell your doctor if you notice any of the following side effects, they get worse or you notice any not listed:
Rare (may affect up to 1 in 1,000 people)
- Allergic reaction (hypersensitivity) e.g. itchy/red skin, rash.
- Severe allergic reaction (anaphylactic reaction) – swelling of the face, lips, tongue or throat or difficulty breathing or swallowing, shock (cold sweaty skin, weak pulse, dry mouth, dilated pupils).
- Stomach and intestines: loss of appetite, feeling sick, a bloated feeling, wind.
How to store Folic Acid tablets
Keep out of the sight and reach of children.
Store below 25°C in a dry place. Protect from light.
What Folic Acid tablets look like and contents of the pack
Folic Acid tablets are yellow, uncoated tablets.
Pack size is 50.
Country of Origin: Turkey
Produced by: ROYVIT PHARMA